Alternative Utilization of Vegetable Crop: Pumpkin Polysaccharide Extract and Their Efficacy on Skin Hydration

Traditional pumpkin (Cucurbita moschata) and Japanese (C. maxima) consist of natural polysaccharides. From a scientific basis, polysaccharides could be applied to improve hydration in the cosmetic field. The purified polysaccharide was extracted deproteinized with CaCl2 method. showed higher value physicochemical properties including yield (12.96 ± 0.60%), total content (0.89 0.04 mg/mL), swelling capacity (4.00 0.00%), index (1.04 solubility (126.67 5.77%), viscosity (1.25 0.00 cps), water (0.93 0.15 g/g) oil absorption (5.93 0.06 than traditional pumpkin. Additionally, (IC50 9.30 0.58 µg/mL) provided antioxidant activity by DPPH assay 9.98 0.25 µg/mL). evaluation efficacy on skin fifteen Thai volunteers indicated that non-skin irritation. An extract concentration 0.05–0.1% significantly increased effect moisturizing ability according (p < 0.05). This result supported it safe effective use as moisturizer for products.